노인환자에게 조심해야 할 약 (미국 노인병 학회 AGS, Beer’s criteria 2023)

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노인환자에게 조심해야 할 약 (미국 노인병학회)

AGS Beers Criteria : Medications considered as potentially inappropriate (PIM)
  • 1세대 anti-histamines : Hydroxyzine 등
  • Nitrofurantoin
  • Aspirin for primary prevention of CV disease
  • Warfarin for the treatment of nonvalvular atrial fibrillation or VTE
  • Rivaroxaban for long-term treatment of nonvalvular atrial fibrillation or VTE
  • Dipyridamole
  • Non-selective peripheral alpha-1 blocker : Doxazoein, Prazosin, Terazosin
  • Central alpha-agonists : clonidine, Guanfacine
  • Nifedipine (속효성)
  • Amiodarone
  • Dronedrone
  • Digoxin
  • Antidepressants with strong anticholinergic activity : Amitriptyline, Amoxapine, Clomipramine, Desipramine, Doxepin (하루 6mg 초과), Imipraine, Nortriptyline, Praxetine
  • Antiparkinsonian agents with strong anticholinergic activity : Benztrophine(경구), Trihexyphenidyl
  • Antipsychotics (1세대, 2세대) : Aripiprazole, Haloperidol, Olanzapine, Quetiapine, Risperidone 등
  • Barbiturates : Butalbital, Phenobarbital, Primidone
  • Benzodiazepines : Alprazolam, Chlordiazepoxide, Clobazam, Clonazepam, Clorazepate, Diazepam, Estazolam, Lorazepam, Midazolam, Oxazepam, Temazepam, Triazolam
  • Nonbenzodiazepine benxodiazepine receptor agonist hypnotics (Z-drugs) : Eszopiclone, Zaleplon, Zolpidem
  • Meprobamate
  • Ergoloid mesylates
  • Androgens : Methyltestosterone, Testosterone
  • Estrogens with/without progestins
  • Insulin, sliding scale
  • Sulfonylurea : Gliclazide, Glimepiride, Glipizide, Glibenclamide
  • Desiccated thyroid
  • Megestrol
  • Growth hormone
  • PPIs : Dexlansoprazole, Esomeprazole, Lansoprazole, Omeprazole, Pantoprazole, Rabeprazole
  •   ; C. difficile 감염 위험 증가, 폐렴, 위장관 종양, bone loss 및 fracture 위험 증가
  • Metoclopramide ; extrapyramidal effect 가능
  • GI antispasmodics with strong anticholinergic activity : Atropine (안약은 제외), Dlidinium-chlordiazepoxide, Dicyclomine, Hyoscyamine, Scopolamine
  • Mineral oil, given orally
  • Desmopressin ; hyponatremia 위험
  • Non-COX-2-selective NSAIDs : Aspirin (하루 325mg 초과시), Diclofenac, Diflunisal, Etodolac, Flurbiprofen, Ibuprofen, Indomethacin, Ketorolac, Meloxicam, Nabumetone, Naproxen, Oxaprozin, Piroxicam, Sulindac
  • Meperidine
  • Skeletal muscle relaxants : Carisoprodol, Chlorzoxazone, Cyclobenzaprine, Metaxalone, Methocarbamol, Orphenadrine

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